The son of Hollywood actor and filmmaker Rob Reiner has been charged with the murder of his parents after they were found dead in their home over the weekend, the Los Angeles Police Department said on Monday.

Nick Reiner, 32, who has struggled with substance abuse, was arrested on Sunday night and is being held in prison with no bail, the police department said in a press release.

Jail documents earlier showed bail had been set at US$4 million. Police found Rob Reiner, 78, the director of beloved films such as When Harry Met Sally … and his wife Michele, 70, dead at their home in the upscale Brentwood neighbourhood of Los Angeles on Sunday afternoon.

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The Los Angeles Police Department said their investigation “determined that the Reiners were the victims of homicide” and that their son “was responsible for their deaths”. Nick Reiner was arrested later on Sunday night.

For years, Nick Reiner, 32, spoke openly about his battles with drug abuse and periods of homelessness when he refused to enter rehab. He told People magazine in a 2016 interview that he first went into rehab for drug abuse at age 15. He eventually had at least 17 stays in facilities.

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Those experiences inspired the film Being Charlie, co-written by Nick Reiner and his father.